Patient Specific 3D Image-Based Radiation Dose Estimates for 90Y Microsphere Hepatic Radioembolization in Metastatic Tumors
نویسندگان
چکیده
منابع مشابه
Determination of Radiation Absorbed Dose to Primary Liver Tumors and Normal Liver Tissue Using Post-Radioembolization 90Y PET
BACKGROUND Radioembolization with Yttrium-90 ((90) Y) microspheres is becoming a more widely used transcatheter treatment for unresectable hepatocellular carcinoma (HCC). Using post-treatment (90) Y positron emission tomography/computerized tomography (PET/CT) scans, the distribution of microspheres within the liver can be determined and quantitatively assessed. We studied the radiation dose of...
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BACKGROUND This paper describes the feasibility of intra-arterial high-activity administration of (188)Re-microspheres. METHODS Patients with unresectable colorectal liver metastases or hepatocellular cancer (HCC) received single treatments with (188)Re-microspheres. The administered activity was calculated to give a liver dose of 100 Gy. From post-therapeutic scans and urine sampling, the do...
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UNLABELLED Absorbed-dose calculations provide a scientific basis for evaluating the biologic effects associated with administered radiopharmaceuticals. In cancer therapy, radiation dosimetry supports treatment planning, dose-response analyses, predictions of therapy effectiveness, and completeness of patient medical records. In this study, we evaluated the organ radiation absorbed doses from in...
متن کاملA Comparison of Techniques for 90Y PET/CT Image-Based Dosimetry Following Radioembolization with Resin Microspheres
(90)Y PET/CT following radioembolization has recently been established as a viable diagnostic tool, capable of producing images that are both quantitative and have superior image quality than alternative (90)Y imaging modalities. Because radioembolization is assumed to be a permanent implant, it is possible to convert quantitative (90)Y PET image sets into data representative of spatial committ...
متن کاملPatient-Specific Radiation Dose and Cancer Risk in Computed Tomography Examinations in Ondo, Nigeria
Introduction: The dose in computed tomography (CT) often approach or exceed the optimum levels, thereby increasing the probability of cancer induction. With wide application of this diagnostic test, it is expedient to determine the effective dose (ED) for each patient to estimate their cancer risk. This study was conducted to investigate the patient-specific dose (PSD) and cancer risk in CT exa...
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ژورنال
عنوان ژورنال: Journal of Nuclear Medicine & Radiation Therapy
سال: 2011
ISSN: 2155-9619
DOI: 10.4172/2155-9619.1000111